Instituto Universitario de Biología Molecular

PUBLICATIONS 2023

 

1

Alanazi A, Jay-Gerin JP, Blázquez-Castro A. Is singlet oxygen involved in FLASH-RT?. J Appl Clin Med Phys. 2023 Jul;24(7):e13974. doi: 10.1002/acm2.13974. Epub 2023 Mar 25. PMID: 36964949 

2

Alfaro-Ruiz R, Aguado C, Martín-Belmonte A, Moreno-Martínez AE, Merchán- Rubira J, Hernández F, Ávila J, Fukazawa Y, Luján R. Different modes of synaptic and extrasynaptic NMDA receptor alteration in the hippocampus of P301S tau transgenic mice. Brain Pathol. 2023 Jan;33(1):e13115. doi: 10.1111/bpa.13115. Epub 2022 Sep 4. PMID: 36058615; PMCID: PMC9836375.

3

Álvarez M, Ruiz-Sala P, Pérez B, Desviat LR, Richard E. Dysregulated Cell Homeostasis and miRNAs in Human iPSC-Derived Cardiomyocytes from a Propionic Acidemia Patient with Cardiomyopathy. Int J Mol Sci. 2023 Jan 22;24(3):2182. doi: 10.3390/ijms24032182. PMID: 36768524; PMCID: PMC9916417.

4

Amils R, Escudero C, Oggerin M, Puente Sánchez F, Arce Rodríguez A, Fernández Remolar D, Rodríguez N, García Villadangos M, Sanz JL, Briones C, Sánchez-Román M, Gómez F, Leandro T, Moreno-Paz M, Prieto-Ballesteros O, Molina A, Tornos F, Sánchez-Andrea I, Timmis K, Pieper DH, Parro V. Coupled C, H, N, S and Fe biogeochemical cycles operating in the continental deep subsurface of the Iberian Pyrite Belt. Environ Microbiol. 2023 Feb;25(2):428-453. doi: 10.1111/1462-2920.16291. Epub 2022 Dec 9. PMID: 36453153; PMCID: PMC10107794. González-de la Fuente S, Requena JM, Aguado B. Datasets of Iso-Seq transcripts for decoding transcriptome complexity in four <i>Leishmania</i> species. Data Brief. 2023 Nov 20;52:109838. doi: 10.1016/j.dib.2023.109838. PMID: 38076479; PMCID: PMC10698239.

5

Andreu S, Ripa I, Bello-Morales R, López-Guerrero JA. Liposomal Lactoferrin Exerts Antiviral Activity against HCoV-229E and SARS-CoV-2 Pseudoviruses In Vitro. Viruses. 2023 Apr 15;15(4):972. doi: 10.3390/v15040972. PMID: 37112952; PMCID: PMC10142420.

6

Andreu S, von Kobbe C, Delgado P, Ripa I, Buzón MJ, Genescà M, Gironès N, Del Moral-Salmoral J, Ramírez GA, Zúñiga S, Enjuanes L, López-Guerrero JA, Bello-Morales R. Dextran sulfate from <i>Leuconostoc mesenteroides</i> B512F exerts potent antiviral activity against SARS-CoV-2 <i>in vitro</i> and <i>in vivo</i>. Front Microbiol. 2023 May 3;14:1185504. doi: 10.3389/fmicb.2023.1185504. PMID: 37206325; PMCID: PMC10189130.

7

Antón-Fernández A, Vallés-Saiz L, Avila J, Hernández F. Neuronal nuclear tau and neurodegeneration. Neuroscience. 2023 May 10;518:178-184. doi: 10.1016/j.neuroscience.2022.07.015. Epub 2022 Jul 22. PMID: 35872252.

8

Archer SDJ, Lee KC, Caruso T, Alcami A, Araya JG, Cary SC, Cowan DA, Etchebehere C, Gantsetseg B, Gomez-Silva B, Hartery S, Hogg ID, Kansour MK, Lawrence T, Lee CK, Lee PKH, Leopold M, Leung MHY, Maki T, McKay CP, Al Mailem DM, Ramond JB, Rastrojo A, Šantl-Temkiv T, Sun HJ, Tong X, Vandenbrink B, Warren-Rhodes KA, Pointing SB. Contribution of soil bacteria to the atmosphere across biomes. Sci Total Environ. 2023 May 1;871:162137. doi: 10.1016/j.scitotenv.2023.162137. Epub 2023 Feb 10. PMID: 36775167.

9

Arribas-Carreira L, Dallabona C, Swanson MA, Farris J, Østergaard E, Tsiakas K, Hempel M, Aquaviva-Bourdain C, Koutsoukos S, Stence NV, Magistrati M, Spector EB, Kronquist K, Christensen M, Karstensen HG, Feichtinger RG, Achleitner MT, Lawrence Merritt Ii J, Pérez B, Ugarte M, Grünewald S, Riela AR, Julve N, Arnoux JB, Haldar K, Donnini C, Santer R, Lund AM, Mayr JA, Rodriguez- Pombo P, Van Hove JLK. Pathogenic variants in GCSH encoding the moonlighting H-protein cause combined nonketotic hyperglycinemia and lipoate deficiency. Hum Mol Genet. 2023 Mar 6;32(6):917-933. doi: 10.1093/hmg/ddac246. PMID: 36190515; PMCID: PMC9990993.

10

Bago Á, Cayuela ML, Gil A, Calvo E, Vázquez J, Queiro A, Schopfer FJ, Radi R, Serrador JM, Íñiguez MA. Nitro-oleic acid regulates T cell activation through post-translational modification of calcineurin. Proc Natl Acad Sci U S A. 202 Jan 24;120(4):e2208924120. doi: 10.1073/pnas.2208924120. Epub 2023 Jan 18. PMID: 36652486; PMCID: PMC9942794.

11

Benayas B, Morales J, Gori A, Strada A, Gagni P, Frigerio R, Egea C, Armisén P, Cretich M, Yáñez-Mó M. Proof of concept of using a membrane-sensing peptide for sEVs affinity based isolation. Front Bioeng Biotechnol. 2023 Aug 11;11:1238898. doi: 10.3389/fbioe.2023.1238898. PMID: 37636002; PMCID: PMC10457001.

12

Biscari L, Maza MC, Farré C, Kaufman CD, Amigorena S, Fresno M, Gironès N, Alloatti A. Sec22b-dependent antigen cross-presentation is a significant contributor of T cell priming during infection with the parasite <i>Trypanosoma cruzi</i>. Front Cell Dev Biol. 2023 Mar 1;11:1138571. doi: 10.3389/fcell.2023.1138571. PMID: 36936692; PMCID: PMC10014565.

13

Callejas-Hernández F, Robello C, Requena JM. Editorial: Protozoan parasites in the multi-omics era: present and future. Front Cell Infect Microbiol. 2023 Sep 14;13:1281638. doi: 10.3389/fcimb.2023.1281638. PMID: 37780851; PMCID: PMC10539553.

14

Calvo-López T, Grueso E, Sánchez-Martínez C, Almendral JM. Intracellular virion traffic to the endosome driven by cell type specific sialic acid receptors determines parvovirus tropism. Front Microbiol. 2023 Jan 23;13:1063706. doi: 10.3389/fmicb.2022.1063706. PMID: 36756201; PMCID: PMC9899843.

15

Camacho E, González-de la Fuente S, Solana JC, Tabera L, Carrasco-Ramiro F, Aguado B, Requena JM. <i>Leishmania infantum</i> (JPCM5) Transcriptome, Gene Models and Resources for an Active Curation of Gene Annotations. Genes (Basel). 2023 Apr 4;14(4):866. doi: 10.3390/genes14040866. PMID: 37107624; PMCID: PMC10137940.

16

Carrasco J, Antón R, Valbuena A, Pantoja-Uceda D, Mukhi M, Hervás R, Laurents DV, Gasset M, Oroz J. Metamorphism in TDP-43 prion-like domain determines chaperone recognition. Nat Commun. 2023 Jan 28;14(1):466. doi: 10.1038/s41467-023-36023-z. PMID: 36709343; PMCID: PMC9884275.

17

Concepción Abrusci, Ricardo Amils, Enrique Sánchez-León. Biodegradation of Choline NTF<sub>2</sub> by <i>Pantoea agglomerans</i> in Different Osmolarity. Characterization and Environmental Implications of the Produced Exopolysaccharide. Polymers (Basel). 2023 Oct 3;15(19):3974. doi: 10.3390/polym15193974. PMID: 37836024; PMCID: PMC10575057.

18

Daddaoua A, Álvarez C, Oggerin M, Rodriguez N, Duque E, Amils R, Armengaud J, Segura A, Ramos JL. Rio Tinto as a niche for acidophilus enzymes of industrial relevance. Microb Biotechnol. 2023 May;16(5):1069-1086. doi: 10.1111/1751-7915.14192. Epub 2023 Feb 7. PMID: 36748404; PMCID: PMC10128141.

19

Del Arco A, González-Moreno L, Pérez-Liébana I, Juaristi I, González- Sánchez P, Contreras L, Pardo B, Satrústegui J. Regulation of neuronal energy metabolism by calcium: Role of MCU and Aralar/malate-aspartate shuttle. Biochim Biophys Acta Mol Cell Res. 2023 Jun;1870(5):119468. doi: 10.1016/j.bbamcr.2023.119468. Epub 2023 Mar 28. PMID: 36997074.

20

Del Puerto A, Lopez-Fonseca C, Simón-García A, Martí-Prado B, Barrios-Muñoz AL, Pose-Utrilla J, López-Menéndez C, Alcover-Sanchez B, Cesca F, Schiavo G, Campanero MR, Fariñas I, Iglesias T, Porlan E. Kidins220 sets the threshold for survival of neural stem cells and progenitors to sustain adult neurogenesis. Cell Death Dis. 2023 Aug 4;14(8):500. doi: 10.1038/s41419-023-05995-7. PMID: 37542079; PMCID: PMC10403621.

21

Domene-Serrano I, Cuadros R, Hernandez F, Avila J, Santa-Maria I. Tridimensional Structural Analysis of Tau Isoforms Generated by Intronic Retention. J Alzheimers Dis Rep. 2023 Nov 22;7(1):1259-1265. doi: 10.3233/ADR-230074. PMID: 38143771; PMCID: PMC10741963.

22

Domingo-Muelas A, Morante-Redolat JM, Moncho-Amor V, Jordán-Pla A, Pérez- Villalba A, Carrillo-Barberà P, Belenguer G, Porlan E, Kirstein M, Bachs O, Ferrón SR, Lovell-Badge R, Fariñas I. The rates of adult neurogenesis and oligodendrogenesis are linked to cell cycle regulation through p27-dependent gene repression of SOX2. Cell Mol Life Sci. 2023 Jan 11;80(1):36. doi: 10.1007/s00018-022-04676-6. PMID: 36627412; PMCID: PMC9832098.

23

Domínguez-Zorita S, Cuezva JM. The Mitochondrial ATP Synthase/IF1 Axis in Cancer Progression: Targets for Therapeutic Intervention. Cancers (Basel). 2023 Jul 25;15(15):3775. doi: 10.3390/cancers15153775. PMID: 37568591; PMCID: PMC10417293.

24

Domínguez-Zorita S, Romero-Carramiñana I, Santacatterina F, Esparza-Moltó PB, Simó C, Del-Arco A, Núñez de Arenas C, Saiz J, Barbas C, Cuezva JM. IF1 ablation prevents ATP synthase oligomerization, enhances mitochondrial ATP turnover and promotes an adenosine-mediated pro-inflammatory phenotype. Cell Death Dis. 2023 Jul 12;14(7):413. doi: 10.1038/s41419-023-05957-z. PMID: 37433784; PMCID: PMC10336053.

25

Escudero C, Amils R. Dark biosphere: Just at the very tip of the iceberg. Environ Microbiol. 2023 Jan;25(1):147-149. doi: 10.1111/1462-2920.16265. Epub 2022 Nov 9. PMID: 36307896; PMCID: PMC10100182.

26

European Alzheimer’s & Dementia Biobank Mendelian Randomization (EADB-MR) Collaboration; Luo J, Thomassen JQ, Bellenguez C, Grenier-Boley B, de Rojas I, Castillo A, Parveen K, Küçükali F, Nicolas A, Peters O, Schneider A, Dichgans M, Rujescu D, Scherbaum N, Jürgen D, Riedel-Heller S, Hausner L, Porcel LM, Düzel E, Grimmer T, Wiltfang J, Heilmann-Heimbach S, Moebus S, Tegos T, Scarmeas N, Clarimon J, Moreno F, Pérez-Tur J, Bullido MJ, Pastor P, Sánchez-Valle R, Álvarez V, Boada M, García-González P, Puerta R, Mir P, Real LM, Piñol-Ripoll G, García-Alberca JM, Royo JL, Rodriguez-Rodriguez E, Soininen H, Kuulasmaa T, de Mendonça A, Mehrabian S, Hort J, Vyhnalek M, van der Lee S, Graff C, Papenberg G, Giedraitis V, Boland A, Bacq-Daian D, Deleuze JF, Nicolas G, Dufouil C, Pasquier F, Hanon O, Debette S, Grünblatt E, Popp J, Benussi L, Galimberti D, Arosio B, Mecocci P, Solfrizzi V, Parnetti L, Squassina A, Tremolizzo L, Borroni B, Nacmias B, Sorbi S, Caffarra P, Seripa D, Rainero I, Daniele A, Masullo C, Spalletta G, Williams J, Amouyel P, Jessen F, Kehoe P, Tsolaki M, Rossi G, Sánchez-Juan P, Sleegers K, Ingelsson M, Andreassen OA, Hiltunen M, Van Duijn C, Sims R, van der Flier W, Ruiz A, Ramirez A, Lambert JC, Frikke-Schmidt R. Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease. JAMA Netw Open. 2023 May 1;6(5):e2313734. doi: 10.1001/jamanetworkopen.2023.13734. Erratum in: JAMA Netw Open. 2023 Jun 1;6(6):e2321189. PMID: 37195665; PMCID PMC10193187.

27

Fairén AG, Rodríguez N, Sánchez-García L, Rojas P, Uceda ER, Carrizo D, Amils R, Sanz JL. Ecological successions throughout the desiccation of Tirez lagoon (Spain) as an astrobiological time-analog for wet-to-dry transitions on Mars. Sci Rep. 2023 Feb 8;13(1):1423. doi: 10.1038/s41598-023-28327-3. PMID: 36755119; PMCID: PMC9908944.

28

Francos-Quijorna I, Carrasco E, Gabandé-Rodríguez E. Editorial: Molecular and epigenetic mechanisms in neuroinflammation and neurodegeneration. Front Aging. 2023 Aug 14;4:1271714. doi: 10.3389/fragi.2023.1271714. PMID: 37645543; PMCID: PMC10461551.

29

Fuertes MA, López Mateos D, Valiente L, Rodríguez Huete A, Valbuena A, Mateu MG. Electrostatic Screening, Acidic pH and Macromolecular Crowding Increase the Self-Assembly Efficiency of the Minute Virus of Mice Capsid In Vitro. Viruses. 2023 Apr 25;15(5):1054. doi: 10.3390/v15051054. PMID: 37243141; PMCID: PMC10224108.

30

Gabandé-Rodríguez E, Pfeiffer M, Mittelbrunn M. Immuno(T)herapy for age- related diseases. EMBO Mol Med. 2023 Jan 11;15(1):e16301. doi: 10.15252/emmm.202216301. Epub 2022 Nov 14. PMID: 36373340; PMCID: PMC9832825.

31

García-Arroyo R, Domènech EB, Herrera-Úbeda C, Asensi MA, Núñez de Arenas C, Cuezva JM, Garcia-Fernàndez J, Pallardó FV, Mirra S, Marfany G. Exacerbated response to oxidative stress in the Retinitis Pigmentosa Cerkl<sup>KD/KO</sup> mouse model triggers retinal degeneration pathways upon acute light stress. Redox Biol. 2023 Oct;66:102862. doi: 10.1016/j.redox.2023.102862. Epub 2023 Aug 28. PMID: 37660443; PMCID: PMC10491808.

32

García-González P, de Rojas I, Moreno-Grau S, Montrreal L, Puerta R, Alarcón-Martín E, Quintela I, Orellana A, Andrade V, Adami PVM, Heilmann- Heimbach S, Gomez-Garre P, Periñán MT, Alvarez I, Diez-Fairen M, Nuñez Llaves R, Olivé Roig C, Garcia-Ribas G, Menéndez-González M, Martínez C, Aguilar M, Buongiorno M, Franco-Macías E, Saez ME, Cano A, Bullido MJ, Real LM, Rodríguez- Rodríguez E, Royo JL, Álvarez V, Pastor P, Piñol-Ripoll G, Mir P, Lara MC, Padilla MM, Sánchez-Juan P, Carracedo A, Valero S, Hernandez I, Tàrraga L, Ramirez A, Boada M, Ruiz A. Mendelian Randomisation Confirms the Role of Y-Chromosome Loss in Alzheimer’s Disease Aetiopathogenesis in Men. Int J Mol Sci. 2023 Jan 4;24(2):898. doi: 10.3390/ijms24020898. PMID: 36674414; PMCID: PMC9863537.

33

González-de la Fuente S, Requena JM, Aguado B. Datasets of Iso-Seq transcripts for decoding transcriptome complexity in four <i>Leishmania</i> species. Data Brief. 2023 Nov 20;52:109838. doi: 10.1016/j.dib.2023.109838. PMID: 38076479; PMCID: PMC10698239.

34

González-Moreno L, Santamaría-Cano A, Paradela A, Martínez-Chantar ML, Martín MÁ, Pérez-Carreras M, García-Picazo A, Vázquez J, Calvo E, González- Aseguinolaza G, Saheki T, Del Arco A, Satrústegui J, Contreras L. Exogenous aralar/slc25a12 can replace citrin/slc25a13 as malate aspartate shuttle component in liver. Mol Genet Metab Rep. 2023 Mar 16;35:100967. doi: 10.1016/j.ymgmr.2023.100967. PMID: 36967723; PMCID: PMC10031141.

35

Guardiola M, Muntané G, Martínez I, Martorell L, Girona J, Ibarretxe D, Plana N, Bullido MJ, Vilella E, Ribalta J. Metabolic Overlap between Alzheimer’s Disease and Metabolic Syndrome Identifies the <i>PVRL2</i> Gene as a New Modulator of Diabetic Dyslipidemia. Int J Mol Sci. 2023 Apr 18;24(8):7415. doi: 10.3390/ijms24087415. PMID: 37108578; PMCID: PMC10139078.

36

Hallsworth JE, Udaondo Z, Pedrós-Alió C, Höfer J, Benison KC, Lloyd KG, Cordero RJB, de Campos CBL, Yakimov MM, Amils R. Scientific novelty beyond the experiment. Microb Biotechnol. 2023 Jun;16(6):1131-1173. doi: 10.1111/1751-7915.14222. Epub 2023 Feb 14. PMID: 36786388; PMCID: PMC10221578.

37

Han K, Singh K, Meadows AM, Sharma R, Hassanzadeh S, Wu J, Goss-Holmes H, Huffstutler RD, Teague HL, Mehta NN, Griffin JL, Tian R, Traba J, Sack MN. Boosting NAD preferentially blunts Th17 inflammation via arginine biosynthesis and redox control in healthy and psoriasis subjects. Cell Rep Med. 2023 Sep 19;4(9):101157. doi: 10.1016/j.xcrm.2023.101157. Epub 2023 Aug 15. PMID: 37586364; PMCID: PMC10518596.

38

Hernández F, Ferrer I, Pérez M, Zabala JC, Del Rio JA, Avila J. Tau Aggregation. Neuroscience. 2023 May 10;518:64-69. doi: 10.1016/j.neuroscience.2022.04.024. Epub 2022 May 4. PMID: 35525497.

39

Horndler L, Delgado P, Romero-Pinedo S, Quesada M, Balabanov I, Laguna-Goya R, Almendro-Vázquez P, Llamas MA, Fresno M, Paz-Artal E, van Santen HM, Álvarez- Fernández S, Olmo A, Alarcón B. Decreased breadth of the antibody response to the spike protein of SARS-CoV-2 after repeated vaccination. Front Immunol. 2023 Apr 3;14:1157263. doi: 10.3389/fimmu.2023.1157263. PMID: 37081876; PMCID: PMC10111966.

40

Jaraíz-Rodríguez M, Del Prado L, Balsa E. Metabolic remodeling in astrocytes: Paving the path to brain tumor development. Neurobiol Dis. 2023 Nov;188:106327. doi: 10.1016/j.nbd.2023.106327. Epub 2023 Oct 13. PMID: 37839712.

41

Labat-de-Hoz L, Rubio-Ramos A, Correas I, Alonso MA. The MAL Family of Proteins: Normal Function, Expression in Cancer, and Potential Use as Cancer Biomarkers. Cancers (Basel). 2023 May 17;15(10):2801. doi: 10.3390/cancers15102801. PMID: 37345137; PMCID: PMC10216460.

42

Lahera A, López-Nieva P, Alarcón H, Marín-Rubio JL, Cobos-Fernández MÁ, Fernández-Navarro P, Fernández AF, Vela-Martín L, Sastre I, Ruiz-García S, Llamas P, López-Lorenzo JL, Cornago J, Santos J, Fernández-Piqueras J, Villa- Morales M. SOCS3 deregulation contributes to aberrant activation of the JAK/STAT pathway in precursor T-cell neoplasms. Br J Haematol. 2023 May;201(4):718-724. doi: 10.1111/bjh.18694. Epub 2023 Feb 14. PMID: 36786170.

43

Lahera A, Vela-Martín L, Fernández-Navarro P, Llamas P, López-Lorenzo JL, Cornago J, Santos J, Fernández-Piqueras J, Villa-Morales M. The JAK3<sup>Q988P</sup> mutation reveals oncogenic potential and resistance to ruxolitinib. Mol Carcinog. 2024 Jan;63(1):5-10. doi: 10.1002/mc.23632. Epub 2023 Sep 15. PMID: 37712558.

44

Lahera A, Vela-Martín L, López-Nieva P, Salgado RN, Rodríguez-Perales S, Torres-Ruiz R, López-Lorenzo JL, Cornago J, Llamas P, Fernández-Navarro P, Sánchez-Domínguez R, Segovia JC, Sastre I, Cobos-Fernández MÁ, Menéndez P, Santos J, Fernández-Piqueras J, Villa-Morales M. Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T-ALL. Br J Haematol. 2023 Aug;202(3):693-698. doi: 10.1111/bjh.18901. Epub 2023 Jun 2. PMID: 37264982.

45

Le Guen Y, Luo G, Ambati A, Damotte V, Jansen I, Yu E, Nicolas A, de Rojas I, Peixoto Leal T, Miyashita A, Bellenguez C, Lian MM, Parveen K, Morizono T, Park H, Grenier-Boley B, Naito T, Küçükali F, Talyansky SD, Yogeshwar SM, Sempere V, Satake W, Alvarez V, Arosio B, Belloy ME, Benussi L, Boland A, Borroni B, Bullido MJ, Caffarra P, Clarimon J, Daniele A, Darling D, Debette S, Deleuze JF, Dichgans M, Dufouil C, During E, Düzel E, Galimberti D, Garcia-Ribas G, García-Alberca JM, García-González P, Giedraitis V, Goldhardt O, Graff C, Grünblatt E, Hanon O, Hausner L, Heilmann-Heimbach S, Holstege H, Hort J, Jung YJ, Jürgen D, Kern S, Kuulasmaa T, Lee KH, Lin L, Masullo C, Mecocci P, Mehrabian S, de Mendonça A, Boada M, Mir P, Moebus S, Moreno F, Nacmias B, Nicolas G, Niida S, Nordestgaard BG, Papenberg G, Papma J, Parnetti L, Pasquier F, Pastor P, Peters O, Pijnenburg YAL, Piñol-Ripoll G, Popp J, Porcel LM, Puerta R, Pérez-Tur J, Rainero I, Ramakers I, Real LM, Riedel-Heller S, Rodriguez- Rodriguez E, Ross OA, Royo LJ, Rujescu D, Scarmeas N, Scheltens P, Scherbaum N, Schneider A, Seripa D, Skoog I, Solfrizzi V, Spalletta G, Squassina A, van Swieten J, Sánchez-Valle R, Tan EK, Tegos T, Teunissen C, Thomassen JQ, Tremolizzo L, Vyhnalek M, Verhey F, Waern M, Wiltfang J, Zhang J; EADB; GR@ACE study group; DEGESCO consortium; DemGene; EADI; GERAD; Asian Parkinson’s Disease Genetics consortium; Zetterberg H, Blennow K, He Z, Williams J, Amouyel P, Jessen F, Kehoe PG, Andreassen OA, Van Duin C, Tsolaki M, Sánchez-Juan P, Frikke Schmidt R, Sleegers K, Toda T, Zettergren A, Ingelsson M, Okada Y, Rossi G, Hiltunen M, Gim J, Ozaki K, Sims R, Foo JN, van der Flier W, Ikeuchi T, Ramirez A, Mata I, Ruiz A, Gan-Or Z, Lambert JC, Greicius MD, Mignot E. Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by <i>HLA-DRB1*04</i> subtypes. Proc Natl Acad Sci U S A. 2023 Sep 5;120(36):e2302720120. doi: 10.1073/pnas.2302720120. Epub 2023 Aug 29. PMID: 37643212; PMCID: PMC10483635.

46

Luque D, Ortega-Esteban A, Valbuena A, Luis Vilas J, Rodríguez-Huete A, Mateu MG, Castón JR. Equilibrium Dynamics of a Biomolecular Complex Analyzed at Single-amino Acid Resolution by Cryo-electron Microscopy. J Mol Biol. 2023 Apr 15;435(8):168024. doi: 10.1016/j.jmb.2023.168024. Epub 2023 Feb 23. PMID: 36828271.

47

Martínez-Pizarro A, Calmels N, Schalk A, Wicker C, Richard E, Desviat LR. Functional analysis of novel variants identified in cis in the PCCB gene in a patient with propionic acidemia. Gene. 2024 Jan 30;893:147902. doi: 10.1016/j.gene.2023.147902. Epub 2023 Oct 13. PMID: 37839763.

48

Matamoros-Recio A, Merino J, Gallego-Jiménez A, Conde-Alvarez R, Fresno M, Martín-Santamaría S. Immune evasion through Toll-like receptor 4: The role of the core oligosaccharides from α2-Proteobacteria atypical lipopolysaccharides. Carbohydr Polym. 2023 Oct 15;318:121094. doi: 10.1016/j.carbpol.2023.121094. Epub 2023 Jun 9. PMID: 37479429.

49

Mateos G, Martínez-Bonilla A, Martínez JM, Amils R. Vitamin B<sub>12</sub> Auxotrophy in Isolates from the Deep Subsurface of the Iberian Pyrite Belt. Genes (Basel). 2023 Jun 26;14(7):1339. doi: 10.3390/genes14071339. PMID: 37510244; PMCID: PMC10378866.

50

Mencía M. Acid digestion and symbiont: Proton sharing at the origin of mitochondriogenesis?: Proton production by a symbiotic bacterium may have been the origin of two hallmark eukaryotic features, acid digestion and mitochondria: Proton production by a symbiotic bacterium may have been the origin of two hallmark eukaryotic features, acid digestion and mitochondria. Bioessays. 2023 Jan;45(1):e2200136. doi: 10.1002/bies.202200136. Epub 2022 Nov 14. PMID: 36373631.

51

Mietzsch M, Qiu J, Almendral JM, Söderlund-Venermo M. Editorial: Parvoviruses: from basic research to biomedical and biotechnological applications. Front Microbiol. 2023 May 15;14:1194926. doi: 10.3389/fmicb.2023.1194926. PMID: 37256056; PMCID: PMC10225675.

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Molinero N, Antón-Fernández A, Hernández F, Ávila J, Bartolomé B, Moreno- Arribas MV. Gut Microbiota, an Additional Hallmark of Human Aging and Neurodegeneration. Neuroscience. 2023 May 10;518:141-161. 

53

Moneo-Corcuera D, Viedma-Poyatos Á, Stamatakis K, Pérez-Sala D. Desmin Reorganization by Stimuli Inducing Oxidative Stress and Electrophiles: Role of Its Single Cysteine Residue. Antioxidants (Basel). 2023 Aug 31;12(9):1703. doi: 10.3390/antiox12091703. PMID: 37760006; PMCID: PMC10525603.

54

Musokhranova U, Grau C, Vergara C, Rodríguez-Pascau L, Xiol C, Castells AA, Alcántara S, Rodríguez-Pombo P, Pizcueta P, Martinell M, García-Cazorla A, Oyarzábal A. Mitochondrial modulation with leriglitazone as a potential treatment for Rett syndrome. J Transl Med. 2023 Oct 26;21(1):756. doi: 10.1186/s12967-023-04622-5. PMID: 37884937; PMCID: PMC10601217.

55

Pastor-Fernández A, Bertos AR, Sierra-Ramírez A, Del Moral-Salmoral J, Merino J, de Ávila AI, Olagüe C, Villares R, González-Aseguinolaza G, Rodríguez MÁ, Fresno M, Gironés N, Bustos M, Smerdou C, Fernandez-Marcos PJ, von Kobbe C. Treatment with the senolytics dasatinib/quercetin reduces SARS-CoV-2-related mortality in mice. Aging Cell. 2023 Mar;22(3):e13771. doi: 10.1111/acel.13771. Epub 2023 Jan 26. PMID: 36704839; PMCID: PMC10014049.

56

Pena-Burgos EM, Regojo RM, Sáenz de Pipaón M, Santos-Simarro F, Ruiz-Sala P, Pérez B, Esteban-Rodríguez MI. Neuropathological Findings in Short-Chain enoyl-CoA Hydratase 1 Deficiency (ECHS1D): Case Report and Differential Diagnosis. Pediatr Dev Pathol. 2023 Mar-Apr;26(2):138-143. doi: 10.1177/10935266221134650. Epub 2022 Dec 14. PMID: 36515364.

57

Pereira MP, García-Bueno B, Caso JR. Editorial: Neuroinflammatory and oxidative/nitrosative pathways in neuropsychiatric and neurological diseases and their possible neuropharmacological regulation, Volume II. Front Pharmacol. 2023 Mar 31;14:1191907. doi: 10.3389/fphar.2023.1191907. PMID: 37063292; PMCID: PMC10102634.

58

Piniella D, Canseco A, Vidal S, Xiol C, Díaz de Bustamante A, Martí-Carrera I, Armstrong J, Bastolla U, Zafra F. Experimental and Bioinformatic Insights into the Effects of Epileptogenic Variants on the Function and Trafficking of the GABA Transporter GAT-1. Int J Mol Sci. 2023 Jan 4;24(2):955. doi: 10.3390/ijms24020955. PMID: 36674476; PMCID: PMC9862756.

59

Piniella D, Zafra F. Functional crosstalk of the glycine transporter GlyT1 and NMDA receptors. Neuropharmacology. 2023 Jul 1;232:109514. doi: 10.1016/j.neuropharm.2023.109514. Epub 2023 Mar 31. PMID: 37003571.

60

Ribeiro AL, Sánchez M, Bosch S, Berenguer J, Hidalgo A. Stabilization of Enzymes by Using Thermophiles. Methods Mol Biol. 2023;2704:313-328. doi: 10.1007/978-1-0716-3385-4_19. PMID: 37642853.

61

Romero-Carramiñana I, Esparza-Moltó PB, Domínguez-Zorita S, Nuevo-Tapioles C, Cuezva JM. IF1 promotes oligomeric assemblies of sluggish ATP synthase and outlines the heterogeneity of the mitochondrial membrane potential. Commun Biol. 2023 Aug 12;6(1):836. doi: 10.1038/s42003-023-05214-1. PMID: 37573449; PMCID: PMC10423274.

62

Salgado B, Sastre I, Bullido MJ, Aldudo J. Herpes Simplex Virus Type 1 Induces AD-like Neurodegeneration Markers in Human Progenitor and Differentiated ReNcell VM Cells. Microorganisms. 2023 May 4;11(5):1205. doi: 10.3390/microorganisms11051205. PMID: 37317179; PMCID: PMC10221020.

63

Sánchez-León E, Huang-Lin E, Amils R, Abrusci C. Production and Characterisation of an Exopolysaccharide by <i>Bacillus amyloliquefaciens</i>: Biotechnological Applications. Polymers (Basel). 2023 Mar 21;15(6):1550. doi: 10.3390/polym15061550. PMID: 36987330; PMCID: PMC10056187.

64

Sánchez-Salvador A, González-de la Fuente S, Aguado B, Yates PA, Requena JM. Refinement of <i>Leishmania donovani</i> Genome Annotations in the Light of Ribosome-Protected mRNAs Fragments (Ribo-Seq Data). Genes (Basel). 2023 Aug Luque D, Ortega-Esteban A, Valbuena A, Luis Vilas J, Rodríguez-Huete A, Mateu MG, Castón JR. Equilibrium Dynamics of a Biomolecular Complex Analyzed at Single-amino Acid Resolution by Cryo-electron Microscopy. J Mol Biol. 2023 Apr 15;435(8):168024. doi: 10.1016/j.jmb.2023.168024. Epub 2023 Feb 23. PMID:36828271.

65

Sanmarco LM, Rone JM, Polonio CM, Fernandez Lahore G, Giovannoni F, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Faust Akl C, Nanda P, Heck ES, Li Z, Lee HG, Chao CC, Rejano-Gordillo CM, Fonseca-Castro PH, Illouz T, Linnerbauer M, Kenison JE, Barilla RM, Farrenkopf D, Stevens NA, Piester G, Chung EN, Dailey L, Kuchroo VK, Hava D, Wheeler MA, Clish C, Nowarski R, Balsa E, Lora JM, Quintana FJ. Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells. Nature. 2023 Aug;620(7975):881-889. doi: 10.1038/s41586-023-06409-6. Epub 2023 Aug 9. PMID: 37558878; PMCID: PMC10725186.

66

Satrustegui J, Larrubia PL, Rodrigues TB, Choi IY, McKenna MC. A tribute to Sebastián Cerdán and his key contributions to brain metabolism. J Neurochem. 2023 May 11. doi: 10.1111/jnc.15828. Epub ahead of print. PMID: 37169729.

67

Sirerol-Piquer MS, Morante-Redolat JM, Porlan E. Editorial: «Unravelling neural stem cell biology: players and strategies». Front Cell Dev Biol. 2023 May 2;11:1206339. doi: 10.3389/fcell.2023.1206339. PMID: 37200629; PMCID: PMC10185880.

68

Spangsberg Petersen US, Dembic M, Martínez-Pizarro A, Richard E, Holm LL, Havelund JF, Doktor TK, Larsen MR, Færgeman NJ, Desviat LR, Andresen BS. Regulating <i>PCCA</i> gene expression by modulation of pseudoexon splicing patterns to rescue enzyme activity in propionic acidemia. Mol Ther Nucleic Acids. 2023 Dec 13;35(1):102101. doi: 10.1016/j.omtn.2023.102101. PMID: 38204914; PMCID: PMC10776996.

69

Strobl K, Mateu MG, de Pablo PJ. Exploring nucleic acid condensation and release from individual parvovirus particles with different physicochemical cues. Virology. 2023 Apr;581:1-7. doi: 10.1016/j.virol.2023.01.010. Epub 2023 Feb 14. PMID: 36842268.

70

Tangeraas T, Constante JR, Backe PH, Oyarzábal A, Neugebauer J, Weinhold N, Boemer F, Debray FG, Ozturk-Hism B, Evren G, Tuba EF, Ummuhan O, Footitt E, Davison J, Martinez C, Bueno C, Machado I, Rodríguez-Pombo P, Al-Sannaa N, De Los Santos M, López JM, Ozturkmen-Akay H, Karaca M, Tekin M, Pajares S, Ormazabal A, Stoway SD, Artuch R, Dixon M, Mørkrid L, García-Cazorla A. BCKDK deficiency: a treatable neurodevelopmental disease amenable to newborn screening. Brain. 2023 Jul 3;146(7):3003-3013. doi: 10.1093/brain/awad010. PMID: 36729635.

71

Toribio V, Yáñez-Mó M. Two Complementary Strategies to Quantitate Extracellular Vesicle Uptake Using Bioluminescence and Non-Lipidic Dyes. Methods Mol Biol. 2023;2668:133-144. doi: 10.1007/978-1-0716-3203-1_11. PMID: 37140795.

72

Tundidor I, Seijo-Vila M, Blasco-Benito S, Rubert-Hernández M, Adámez S, Andradas C, Manzano S, Álvarez-López I, Sarasqueta C, Villa-Morales M, González- Lois C, Ramírez-Medina E, Almoguera B, Sánchez-López AJ, Bindila L, Hamann S, Arnold N, Röcken C, Heras-Murillo I, Sancho D, Moreno-Bueno G, Caffarel MM, Guzmán M, Sánchez C, Pérez-Gómez E. Identification of fatty acid amide hydrolase as a metastasis suppressor in breast cancer. Nat Commun. 2023 May 30;14(1):3130. doi: 10.1038/s41467-023-38750-9. PMID: 37253733; PMCID: PMC10229544.

73

Úbeda M, Maza MDC, Delgado P, Horndler L, Abia D, García-Bermejo L, Serrano-Villar S, Calvo C, Bastolla U, Sainz T, Fresno M. Diversity of immune responses in children highly exposed to SARS-CoV-2. Front Immunol. 2023 Mar 3;14:1105237. doi: 10.3389/fimmu.2023.1105237. PMID: 36936972; PMCID: PMC10020361.

74

Valbuena A, Strobl K, Gil-Redondo JC, Valiente L, de Pablo PJ, Mateu MG. Single-Molecule Analysis of Genome Uncoating from Individual Human Rhinovirus Particles, and Modulation by Antiviral Drugs. Small. 2023 Oct 8:e2304722. doi: 10.1002/smll.202304722. Epub ahead of print. PMID: 37806749.

75

Vallés-Saiz L, Ávila J, Hernández F. Lamivudine (3TC), a Nucleoside Reverse Transcriptase Inhibitor, Prevents the Neuropathological Alterations Present in Mutant Tau Transgenic Mice. Int J Mol Sci. 2023 Jul 6;24(13):11144. doi: 10.3390/ijms241311144. PMID: 37446327; PMCID: PMC10342792.

76

Villa-Morales M, Pérez-Gómez L, Pérez-Gómez E, López-Nieva P, Fernández- Navarro P, Santos J. Identification of NRF2 Activation as a Prognostic Biomarker in T-Cell Acute Lymphoblastic Leukaemia. Int J Mol Sci. 2023 Jun 19;24(12):10350. doi: 10.3390/ijms241210350. PMID: 37373496; PMCID: PMC10299336.

77

Yáñez-Mó M, Siljander PR. Editorial- Insights of extracellular vesicles in cell biology. Eur J Cell Biol. 2023 Sep;102(3):151327. doi: 10.1016/j.ejcb.2023.151327. Epub 2023 Jun 7. PMID: 37330395.