Instituto Universitario de Biología Molecular

PUBLICATIONS 2025

Authors

Title

Year

Publication

Volume

Page start

Page end

DOI

Akdeniz BC y cols (Bullido, M.J).  

Polygenic Hazard Score for Predicting Age-associated Risk of Alzheimer’s Disease in European Populations: Development and Validation.

2025

medRxiv [Preprint]

 

 

 

10.1101/2025.07.28.25332293

Alcover-Sanchez, B.; Garcia-Martin, G.; Paleo-García, V.; Quintas, A.; Dopazo, A.; Gruart, A.; Delgado García, J.M.; de la Villa, P.; Wandosell, F.; Pereira, M.P.; Cubelos, B.

R-Ras1 and R-Ras2 regulate mature oligodendrocyte subpopulations

2025

GLIA

73

701

719

10.1002/glia.24643

Andreu S, Tang K, Zhou J, Pino-Peco G, López-Carrobles N, Bello-Morales R, Galdo-Torres D, Zhang L, Gago F, López-Guerrero JA, Liu X, Zhan P, Menéndez- Arias L.

Discovery of a Baloxavir-Inspired Endonuclease Inhibitor That Prevents Herpes Simplex Virus 1 Replication in Cell Culture and In Vivo.

2025

Adv Sci (Weinh)

12

e08006

 

10.1002/advs.202508006

Andreu, S.; Galdo-Torres, D.; Ripa, I.; Caballero, O.; Bello-Morales, R.; López-Guerrero, J.A.

From HSV-2 to HSV-1: A change in the epidemiology of genital herpes

2025

J. Infect.

91

 

 

10.1016/j.jinf.2025.106636

Anton-Fernandez A, Domene-Serrano I, Cuadros R, Peinado-Cahuchola R, Sanchez- Pece M, Hernandez F, Avila J.

Peptide Family Promotes Brain Cell Rejuvenation and Improved Cognition through Peripheral Delivery.

2025

 ACS Omega

10

13236

13250

 

Anton-Fernandez, A.; Cauchola, R.P.; Hernández, F.; Avila, J.

Hippocampal rejuvenation by a single intracerebral injection of one-carbon metabolites in C57BL6 old wild-type mice

2025

Aging Cell

24

 

 

10.1111/acel.14365

Anton-Fernandez, A.; Domene-Serrano, I.; Cuadros, R.; Peinado-Cahuchola, R.; Sanchez-Pece, M.; Hernández, F.; Avila, J.

Peptide Family Promotes Brain Cell Rejuvenation and Improved Cognition through Peripheral Delivery

2025

ACS Omega

10

13236

13250

10.1021/acsomega.4c10849

Anton-Fernandez, A.; Ruiz de Alegría, Á.; Mariscal-Casero, A.; Roldán-Lázaro, M.; Peinado-Cauchola, R.; Avila, J.; Hernández, F.

Partial reprogramming by cyclical overexpression of Yamanaka factors improves pathological phenotypes of tauopathy mouse model of human Alzheimer’s disease

2025

Progress in Neurobiology

247

 

 

10.1016/j.pneurobio.2025.102743

Asensio, A.; Sanz-Flores, M.; Liakath-Ali, K.; Romo-Gallo, A.; Palacios-García, J.; Paramio, J.M.; Garcia-Escudero, R.; Mayor, F.; Ribas, C.

The G-Protein-Coupled Receptor Kinase 2 Orchestrates Hair Follicle Homeostasis

2025

J. Invest. Demartol.

 

 

 

10.1016/j.jid.2025.08.040

Avila, J.; Hernández, F.; PERRY, G.

Amyloid and tau pathologies cross-talk to promote Alzheimeŕs disease: novel mechanistic insights

2025

Neuroscience

582

58

62

10.1016/j.neuroscience.2025.07.025

Benayas, B.; Sánchez-Herrero, E.; Robado de Lope, L.; Morales, J.; López-Martín, S.; Provencio Pulla, M.; Valés-Gómez, M.; Romero, A.; Yáñez-Mó, M.

Optimized size exclusion chromatography demonstrates that extracellular vesicles are the key RNA carriers of ALK translocations in non-small cell lung cancer cell line secretome and patient plasma

2025

Extracellular Vesicles and Circulating Nucleic Acids 

6

310

323

10.20517/evcna.2025.14

Berlanga, J.J.; Matamoros, T.; Pulido, M.R.; Sáiz, M.; Bayón, M.N.; Toribio, R.; Ventoso, I.

The differential effect of SARS-CoV-2 NSP1 on mRNA translation and stability reveals new insights linking ribosome recruitment, codon usage, and virus evolution

2025

Nucleic Acids Res.

53

 

 

10.1093/nar/gkaf261

Blas-Muñoz L, Orrego AH, Hofmeister M, Martínez-Salvador J, Ortega C, Rondón Berrio V, Díaz-Rullo J, Finnigan J, Charnock S, Fessner WD, González-Pastor JE, Hidalgo A. 

A Microfluidics-Based Ultrahigh -Throughput Screening Unveils Diverse Ketoreductases Relevant to Pharmaceutical Synthesis.

2025

Anal Chem

97

20698

20706

 10.1021/acs.analchem.5c01029

Blesa, A.; Sánchez-Costa, M.; Berenguer, J.

The PulE ATPase is required for twitching motility and DNA donation during Thermus thermophilus transjugation

2025

Int. Microbiol.

28

1047

1055

10.1007/s10123-024-00598-4

Bottaro, M.; Abramov, S.; Amils, R.; Straub, D.; Kühnel, S.; Mollenkopf, M.; Kleindienst, S.; Obst, M.; Kappler, A.

Impact of pH and salinity fluctuations on oxidation of Fe(II) by nitrate-reducing microorganisms enriched from the reduced tidal sediment of an extreme acidic river (Río Tinto, Spain)

2025

FEBS Microbiol Ecology

101

 

 

10.1093/femsec/fiaf083

Bracher-Smith, M y cols (Bullido, M.J).  

Machine learning in Alzheimer’s disease genetics

2025

Nat. Commun.

16

 

 

10.1038/s41467-025-61650-z

Cai, Q.; Zhao, W.; Wang, J.; Yang, G.; Amils, R.; Martínez, J.M.; Mateos, G.; Carrasco-Ropero, I.; Wu, J.; Xu, M.

A cooperation mechanism between Bacillus thuringiensis and Citrobacter freundii that enhances cadmium biomineralization

2025

Journal of Hazardous Materials

488

 

 

10.1016/j.jhazmat.2025.137354

Callejas-Hernández, F.; Herreros-Cabello, A.; Poveda, C.; Maza, M.C.; Mares, J.F.; Santos-Peñaloza, D.K.; Fresno, M.; Gironès, N.

RNA Sequence Analysis in Macrophages Infected With Trypanosoma cruzi: Focus on TLR2 and TLR7, Iron Metabolism, and Extracellular Matrix Biosynthesis

2025

J. Infect. Dis

231

e1102

e1113

10.1093/infdis/jiaf074

Calvo-López, T.; Grueso, E.; Sánchez-Martínez, C.; Almendral, J.M.

Correction: Intracellular virion traffic to the endosome driven by cell type specific sialic acid receptors determines parvovirus tropism (Frontiers in Microbiology, (2023), 13, (1063706), 10.3389/fmicb.2022.1063706)

2025

Frontiers in Microbiol.

16

 

 

10.3389/fmicb.2025.1640264

Cámara-Checa, A.y cols (Richard, E)

Propionic Acidemia-Induced Proarrhythmic Electrophysiological Alterations in Human iPSC-Derived Cardiomyocytes

2025

J. Inherited Metabolic Dis.

48

 

 

10.1002/jimd.70030

Cavazza, A. y cols (Richard, E)

Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group

2025

Molecular Therapy Nucleic Acids

36

 

 

10.1016/j.omtn.2025.102457

Cruchaga C y cols (Bullido, M.J). 

GWAS meta-analysis of CSF Alzheimer’s disease biomarkers 18,948 individuals reveal novel loci and genes regulating lipid metabolism, brain volume and autophagy.

2025

Res Sq [Preprint]

21

rs.3.rs-6597595

 

10.21203/rs.3.rs-6597595/v1

Cuesta, N.; Staniszewska, A.D.; Moreno, C.; Punzón, C.; Fresno, M.

NF-κB-Inducing Kinase Is Essential for Effective c-Rel Transactivation and Binding to the Il12b Promoter in Macrophages

2025

Biology

14

 

 

10.3390/biology14010033

de Andrés, R.; Martínez-Blanco, E.; Diez-Guerra, F.J.

HDAC4 Inhibits NMDA Receptor-mediated Stimulation of Neurogranin Expression

2025

Mol. Neurobiol.

62

5609

5628

10.1007/s12035-024-04598-3

de las Heras, M.M.G.; Carrasco, E.; Pérez-Manrique, M.; Inohara, N.; Delgado-Pulido, S.; Fernández-Almeida, Á.; Gálvez-Castaño, M.I.; Francos-Quijorna, I.; Simó, C.; García-Cañas, V.; Escrig-Larena, J.I.; Aranda, J.F.; Soto-Heredero, G.; Gabandé-Rodríguez, E.; Blanco, E.M.; Dias-Almeida, J.; Núñez, G.; Mittelbrunn, M.

CD4 T cell therapy counteracts inflammaging and senescence by preserving gut barrier integrity

2025

Sci. Immunol.

10

 

 

10.1126/sciimmunol.adv0985

Díaz-Rullo, J.; González-Moreno, L.; del Arco Martínez, A.; González-Pastor, J.E.

Decoding the general role of tRNA queuosine modification in eukaryotes

2025

Sci. Rep.

15

 

 

10.1038/s41598-024-83451-y

Domene-Serrano, I.; Cuadros, R.; García-Escudero, V.; Vallejo-Bedia, F.; Santa-María, I.; Vallés-Saiz, L.; Hernández, F.; Avila, J.

Shapeshifter W-Tau Peptide Inhibits Tau Aggregation and Disintegrates Paired Helical Filaments

2025

Biochemistry

64

1841

1851

10.1021/acs.biochem.4c00809

Elena Martín-Hernández y cols (B. Pérez).

Understanding the natural history and the effects of current therapeutic strategies on urea cycle disorders: insights from the UCD Spanish registry.

2025

Nutrients

7

 1173

 

10.3390/nu17071173

Escrig, J.; Gil-Redondo, J.C.; Valbuena, A.; Mateu, M.G.

Engineering mechanical strength and resistance to fatigue of a nanostructured protein material through genetic removal of electrostatic repulsions

2025

Nanoscale

17

20157

20168

10.1039/d5nr02490k

Esteban-Ortega, G.M.; Garcia-Martin, G.; Cubelos, B.

Novel Animal Models for Multiple Sclerosis: R-Ras GTPases in Myelin Pathophysiology

2025

Biomolecules

15

 

 

10.3390/biom15091309

Galdo-Torres D, Andreu S, Caballero O, Hernández-Ruiz I, Ripa I, Bello- Morales R, López-Guerrero JA.

 Immune Modulatory Effects of Vitamin D on Herpesvirus Infections.

2025

.Int J Mol Sci

19

1767

 

10.3390/ijms26041767

Gallego-Rentero, M.; Botella, L.M.; Mascaraque, M.; Nicolás-Morala, J.; Albiñana, V.; Abarca-Lachen, E.; Gilaberte, Y.; González, S.; Juarranz, Á.; Carrasco, E.

N-acetylcysteine and raloxifene boost photodynamic therapy against cutaneous squamous cell carcinoma by decreasing TGFβ1 secreted by cancer-associated fibroblasts

2025

Inter. J. Biol. Sci.

21

3164

3182

10.7150/ijbs.106642

Garcia-González, P. y cols (Bullido, M.J)

A Spanish-Portuguese GWAS of progressive supranuclear palsy reveals a novel risk locus in NFASC

2025

European Journal of Human Genetics

33

960

965

10.1038/s41431-025-01872-3

García-Tenorio, E.M.; Álvarez, M.; Gallego-Bonhomme, M.; Desviat, L.R.; Richard, E.

Novel CRISPR-Cas9 iPSC knockouts for PCCA and PCCB genes: advancing propionic acidemia research

2025

Human Cell

38

 

 

10.1007/s13577-025-01193-z

Gil-Redondo, J.C.; Valiente, L.; Riomoros-Barahona, V.; Valbuena, A.; Mateu, M.G.

Human Rhinovirus B14 with Non-functional Drug-binding Pockets Recovers Infectivity through Stereochemically Constrained Mutations that Restore Capsid Flexibility

2025

J. Mol. Biol.

437

 

 

10.1016/j.jmb.2025.169260

Gómez de las Heras, M.M.; Carrasco, E.; Pérez-Manrique, M.; Inohara, N.; Delgado-Pulido, S.; Fernández-Almeida, Á.; Gálvez-Castaño, M.I.; Francos-Quijorna, I.; Simó, C.; García-Cañas, V.; Escrig-Larena, J.I.; Aranda, J.F.; Soto-Heredero, G.; Gabandé-Rodríguez, E.; Blanco, E.M.; Dias-Almeida, J.; Núñez, G.; Mittelbrunn, M.

CD4 T cell therapy counteracts inflammaging and senescence by preserving gut barrier integrity

2025

Sci. Immunol.

10

eadv0985

 

10.1126/sciimmunol.adv0985

Gonzalez-Garcia, M.C.; Ballesteros, D.; Hernandez, J.J.; Pazos, M.; Rodríguez, I.; Requejo-Isidro, J.; Flors, C.

Exploring bacteria–surface interactions with a fluorescent membrane tension probe

2025

Proc. Nat. Acad. Sci.

122

 

 

10.1073/pnas.2512977122

Hernandez-Rocamora V, Martorana AM, Belloso A, Ballesteros D, Zaccaria M, Perez AJ, Iorga BI, Abia D, Gray J, Breukink E, Xiao J, Pazos M, Polissi A, Vollmer W.

A novel peptidoglycan deacetylase modulates daughter cell separation in E. coli.

2025

bioRxiv [Preprint].

19

 

 

10.1101/2025.02.18.638797

Herreros-Cabello, A.; Callejas-Hernández, F.; Fresno, M.; Gironès, N.

Mitochondrial DNA Structure in Trypanosoma cruzi

2025

Pathogens.

14

 

 

10.3390/pathogens14010073

Herreros-Cabello, A.; Callejas-Hernández, F.; Gironès, N.; Fresno, M.

Trypanosoma cruzi: Genomic Diversity and Structure

2025

Pathogens.

14

 

 

10.3390/pathogens14010061

Lahera, A.; Vela-Martín, L.; Fernández-Navarro, P.; López-Lorenzo, J.L.; Cornago-Navascués, J.; Llamas, P.; Fresno, M.; Santos, J.; Villa-Morales, M.

Improved identification of T-ALL paediatric patients with low MRD but poor prognosis using a transcriptional signature

2025

British J. Haematol.

207

2147

2152

10.1111/bjh.70118

Le Borgne J,  y cols (Bullido, M.J). .

  X-chromosome-wide association study for Alzheimer’s disease

2025

Mol Psychiatry

30

2335

2346

10.1038/s41380-024-02838-5

Ledesma-Terrón M, Pérez-Dones D, Mazo-Durán D, Navarro-Martinez G, Gíron GG  Míguez DG. 

Object Stitching by Clustering of Adjacent Regions for accurate quantification of three-dimensional tissues

2025

J Cell Sci. 

138

jcs264316

 

 

Lorente-Arevalo, Á.; Gimeno-Perez, M.; Ortega, C.; Finnigan, J.; Charnock, S.; Hidalgo, A.

Ultrahigh-throughput screening assay for PET-degrading enzymes

2025

Methods Enzimol.

714

489

503

10.1016/bs.mie.2025.01.021

M.A. Martínez Olmos, E. Venegas Moreno, M. Morales Conejo, L. Ceberio Hualde, B. Pérez, M. de Tallo Forga, F.J. Pérez-Sádaba, P. Correcher Medina.

Clinical characteristics and management of Spanish adult patients with phenylketonuria

2025

Rev Clin Esp

8

 502356

 

10.1016/j.rceng.2025 40850348

Martínez-Blanco E, de Andrés R, Baratas-Álvarez L, Díez-Guerra FJ. CaMK2rep:.

Object Stitching by Clustering of Adjacent Regions for accurate quantification of three-dimensional tissues.

2025

Anal Chem

97

20275

20290

10.1021/acs.analchem.5c03227

Martínez-Ranz M, Kidibule PE, Jiménez-Ortega E, Valcárcel J, Vázquez JA, Sanz-Aparicio J, Fernández-Lobato M. 

Boosting Biocatalytic Efficiency: Engineering of Chitinase Chit33 with Chitin and Cellulose Binding Domains for Sustainable Chitin Conversion.

2025

J Agric Food Chem.

73

11121

11131

10.1021/acs.jafc.4c10364.

Martín-Sánchez, J.; Requena, J.M.; Gállego, M.; Jiménez, M.; Molina, R.; Nguewa, P.; Morillas-Márquez, F.; Pérez-Victoria, J.M.; Monge-Maíllo, B.; Morales-Yuste, M.; Marín, C.

Agreement Document for the Study of Leishmaniasis from a One Health Approach in Spain

2025

Trop. Med. Infect. Dis.

10

 

 

10.3390/tropicalmed10090269

Merino-Serrais, P.; Soria, J.M.; Arrabal, C.A.; Ortigado-López, A.; García-Esparza, M.Á.G.; Múñoz, A.; Hernández, F.; Avila, J.; DeFelipe-Oroquieta, J.; León-Espinosa, G.

Protein tau phosphorylation in the proline rich region and its implication in the progression of Alzheimer’s disease

2025

Experimentaly Neurology.

383

 

 

10.1016/j.expneurol.2024.115049

Minguet-Lobato M, Fernández-García Á, Jiménez-Ortega E, Cervantes FV, Sánchez-Pozo P, Plou FJ, Sanz-Aparicio J, Fernández-Lobato M.

Structural- mechanistic insights and performance engineering of chitinase MpChit35 for tailored chito-oligosaccharide production.

2025

Int J Biol Macromol.

322

146538

 

 10.1016/j.ijbiomac.2025

Morin, E.; Doumard, E.; Hartnell, L.M.; Salegi Ansa, B.; Leduc-Gaudet, J.-P.; Quillien, A.; Nakhle, J.; Ethuin, S.; Goudounèche, D.; Payré, B.; Soldan, V.; Balor, S.; Mattout, A.; Rouquette, J.; Dubois, L.; Sengenès, C.; Planat, V.; Casteilla, L.; Yart, A.; Dray, C.; Aligon, J.; Ferrucci, L.; Duchesne, É.; Hussain, S.N.A.; Gouspillou, G.; Formentini, L.; Mourier, A.; Baris, O.R.; Valet, P.; Parpex, H.; Monsarrat, P.; Vigneau, M.; Pradère, J.-P.

EMito-Metrix enables automated evaluation of mitochondrial morphology across species

2025

Nat. Metabolism

7

2179

2182

10.1038/s42255-025-01400-z

Nicolas, A. y cols (Bullido M.J.)

Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations

2025

Nat. Genetic

57

1598

1610

10.1038/s41588-025-02227-w

Palma-Cobo, M.; Toribio, V.; Morales, J.; López-Martín, S.; Enrich, C.; Lu, A.; Yáñez-Mó, M.

Genome-Wide CRISPR/Cas9 Screening Identifies the COMMANDER Recycling Complex as a Key Player in EV Uptake

2025

J. Extracell. Vesicles

14

 

 

10.1002/jev2.70166

Pascoal C, Granjo P, Mexia P, Gallego D, Adubeiro Lourenço R, Sharma S, Pérez B, Castro-Caldas M, Grosso AR, Dos Reis Ferreira V, Videira PA.

Unraveling the biological potential of skin fibroblast: responses to TNF-α, highlighting intracellular signaling pathways and secretome.

2025

Inmmunol. Lett

276

107057

 

10.1016/j.imlet.2025.107057

Pérez-Dones, D.; Mazo-Durán, D.; Míguez, D.G.

Modeling and Analyzing Biological Systems Using Branching Processes

2025

SEMA SIMAI Springer Series

40

83

105

10.1007/978-3-031-99044-1_4

Puerta, R. y cols (Bullido, M.J).

Linking genomic and proteomic signatures to brain amyloid burden: insights from GR@ACE/DEGESCO

2025

Functional and Integrative Genomics

25

 

 

10.1007/s10142-025-01581-6

Rapún J, Pérez-Martín S, Cámara-Checa A, San José G, Núñez-Fernández R, Crespo-García T, Hoban A, Rubio-Alarcón M, Martínez-Blanco E, Tamargo J, Díez- Guerra FJ, López B, Gómez R, González A, Delpón E, Caballero R. 

Two concurrent mechanisms are responsible for the I<sub>Na</sub> increase produced by dapagliflozin and empagliflozin in healthy and heart failure cardiomyocytes.

2025

Biomed Pharmacother

186

117984

 

 10.1016/j.biopha.2025

Reglero-Real, N.; Rolas, L.; Nourshargh, S.

Aging microvasculature: Effects on immune cell trafficking and inflammatory diseases

2025

J. Exp. Med.

222

 

 

10.1084/jem.20242154

Ripa I, Andreu S, Galdo D, Caballero O, Bello-Morales R, López-Guerrero JA.

Polyclonal LC3B Antibodies Generate Non-Specific Staining in the Nucleus of Herpes Simplex Virus Type 1-Infected Cells: Caution in the Interpretation of LC3 Staining in the Immunofluorescence Analysis of Viral Infections.

2025

Int J Mol Sci.

26

6682

 

10.3390/ijms26146682

Ripa, I.; Andreu, S.; Galdo, D.; Caballero, O.; Bello-Morales, R.; López-Guerrero, J.A.

Polyclonal LC3B Antibodies Generate Non-Specific Staining in the Nucleus of Herpes Simplex Virus Type 1-Infected Cells: Caution in the Interpretation of LC3 Staining in the Immunofluorescence Analysis of Viral Infections

2025

Int. J. Mol. Sci.

26

 

 

10.3390/ijms26146682

Rivas-Santisteban, J.; Martínez, J.M.; Escudero, C.; Hernández-Antolín, R.; Cid-Barrio, L.; Ellis, G.J.; Domingo, E.; Sánchez, C.; Sobrino, F.; Amils, R.

Metagenomic analysis of heavy water-adapted bacterial communities

2025

Microbial. Genomics

11

 

 

10.1099/mgen.0.001414

Rodriguez-Baili, M.C.; Palma-Cobo, M.; Prucca, C.G.; Yáñez-Mó, M.; Gil, G.A.

Intercellular communication between extracellular vesicles from conditioned macrophages and breast cancer cells drives endocrine therapy resistance

2025

Front. Cell. Develop. Biol.

13

 

 

10.3389/fcell.2025.1548724

Sabroso, E.; Martínez, J.M.; Sánchez-León, E.; Rodríguez, N.; Amils, R.; Abrusci, C.

Production and Characterisation of an Exopolysaccharide by Vreelandella titanicae Zn11_249 Isolated from Salar de Uyuni (Bolivia)

2025

Polymers

17

 

 

10.3390/polym17172362

Santi-Rocca, J.; Martín-García, D.F.; Lorca-Alonso, I.; la González-de la Fuente, S.; Aguado, B.; Bonner, M.; Amard, V.; Amiot, P.; Bar, C.; Berbon, V.; Berkani, N.; Burke, A.; Cartagena, I.; Chatard, J.-M.; Coutayar, C.; Depraz, G.; Morales, I.; Popa, N.; Regniers, S.; Rissoan, T.; Robert, C.; Tremoureux, A.; Verdy, M.; Fresno, M.; Gironès, N.

Microbial Complexes in Subgingival Plaque: A Bacterial Meta-Taxonomic Study

2025

J. Clin. Periodontol.

52

983

998

10.1111/jcpe.14138

Sarmiento-Jiménez, J.; Felipe, R.; Núñez, E.; Ferrando-Muñoz, A.; Benito-Muñoz, C.; Gago, F.; Vázquez, J.; Camafeita, E.; Clement, E.; Wilson, B.; López‑Corcuera, B.

A New GlyT2 Variant Associated with Hyperekplexia

2025

Int. J. Mol. Sci.

26

 

 

10.3390/ijms26146753

Sebastián-Serrano Á, Simón-García A, Santos-Galindo M, Sánchez-Carralero MP, H-Alcántara A, Clemente C, Pose-Utrilla J, Campanero MR, Porlan E, Lucas JJ, Iglesias T.

Down-regulation of neuroprotective protein kinase D in Huntington´s disease

2025

Cell Death Dis.

16

418

 

10.1038/s41419-025-07688-9.

Segovia, J.C.; J.C.; Río, P.; Lotufo, C.M.; López-Bueno, A.; Calvo-López, T.; Lamana, M.L.; Sandonís, V.; Balas, A.; Bautista-Santa Cruz, J.M.; Abad, P.; Azcárate, I.G.; J.L.; Jalilian, F.A.; Amini, R.; Kinnunen, P.M.; Jokelainen, P.; Mohanraj, U.; Söderlund-Venermo, M.; Almendral, J.M.

A presumed mouse parvovirus with overlooked high toxicity for human primitive CD34+ hematopoietic precursors in vitro and in bone marrow-humanized mice

2025

Microbiol. Spectrum

13

1

23

10.1128/spectrum.02339-25

Sevilla-Lorente, R.; Marmol-Perez, A.; González-García, P.; Rodríguez-Miranda, M.D.L.N.; Riquelme-Gallego, B.; Aragón-Vela, J.; Martinez-Galvez, J.M.; Molina-Garcia, P.; Alcantara, J.M.A.; García-Consuegra, J.; Cogliati, S.; Salmerón, L.M.; Huertas, J.R.; López, L.C.; Ruíz, J.R.; Amaro-Gahete, F.J.

Sexual dimorphism on the acute effect of exercise in the morning vs. evening: A randomized crossover study

2025

Journal of Sport and Health Science

14

 

 

10.1016/j.jshs.2024.101021

Sonustun B, Vahsen BF, Ledesma-Terrón M, Li Z, Tuffery L, Xu N, Calder EL, Jungverdorben J, Weber L, Zhong A, Miguez DG, Monetti M, Zhou T, Giacomelli E, Studer L.

Telmisartan is neuroprotective in a hiPSC-derived spinal microtissue model for C9orf72 ALS via inhibition of neuroinflammation.

2025

Stem Cell Reports

20

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Soto-Heredero G, Gabandé-Rodríguez E, Carrasco E, Escrig-Larena JI, Gómez de Las Heras MM, Delgado-Pulido S, Francos-Quijorna I, Blanco EM, Fernández-Almeida Á, Abia D, Rodríguez MJ, Fernández-Díaz CM, Álvarez-Flores MB, Ramírez de Molina A, Jung S, Del Sol A, Zorita V, Sánchez-Cabo F, Torroja C, Mittelbrunn M.

KLRG1 identifies regulatory T cells with mitochondrial alterations that accumulate with aging.

2025

Nat Aging

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 APOE  stratified genome-wide association studies provide novel insights into the genetic etiology of Alzheimers’s disease.

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medRxiv [Preprint]

 

 

 

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Ulecia-Morón, C.; Bris, Á.G.; MacDowell, K.S.; Cerveró-García, P.; Madrigal, J.L.M.; García-Bueno, B.; Pereira, M.P.; Leza, J.C.; Caso, J.R.

Chronic mild stress dysregulates autophagy, membrane dynamics, and lysosomal status in frontal cortex and hippocampus of rats

2025

Eur. Neuropsychopharmacol.

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Valiente, L.; Riomoros-Barahona, V.; Gil-Redondo, J.C.; Castón, J.R.; Valbuena, A.; Mateu, M.G.

A RNA Dodecahedral Cage Inside a Human Virus Plays a Dual Biological Role in Virion Assembly and Genome Release Control

2025

J. Mol. Biol.

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10.1016/j.jmb.2024.168922

Vallés-Saiz L, Domene-Serrano I, Picher AJ, Pérez M, García-Escudero V, Hernández F, Avila J. 

Structure and function of Full-length Tau.

2025

PLoS One

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Vallés-Saiz, L.; Abdelkader-Guillén, A.; Avila, J.; Hernández, F.

Retrotransposon Protein L1 ORF1p Expression in Aging Central Nervous System

2025

Int. J. Mol. Sci.

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Vega-Cuesta, P.; Pulido, D.; Abia, D.; Herrera, S.; López-Varea, A.; Ruíz Gómez, A.; Fernández Freire, P.; Peropadre, A.; de Celis, J.F.

A Drosophila ecdysone-deficient model to assess the endocrine disruptor activity of Bisphenol A

2025

Ecotoxicology and Environmental Safety

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Codon Usage Bias in Human RNA Viruses and Its Impact on Viral Translation, Fitness, and Evolution

2025

Viruses

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10.3390/v17091218

Villa-Gonzalez, M.; García-Juan, M.; Ordóñez-Gutiérrez, L.; Pérez-Álvarez, M.J.; Jurado, F.W.

HIF-1α downregulates the APP protein after oxygen and glucose deprivation in the APPswe/PSEN1 mouse model of Alzheimer’s disease

2025

Neurochem. Inter.

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Zamora-Dorta, M.; Laine-Menéndez, S.; Abia, D.; González-García, P.; López, L.C.; Fernández-Montes, P.; Calvo, E.; Vázquez, J.; Enríquez, J.A.; Balsa, E.

Time-resolved mitochondrial screen identifies regulatory components of oxidative metabolism

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A Chromatic Nanoswitcher for Thermal Monitoring of Cell Metabolism

2025

Advanced Functional Materials

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